Detection of metallo β-lactamase producing Klebsiella pneumoniae in a neonatal septicemia
نویسندگان
چکیده
منابع مشابه
Isolation of the first IMP-4 metallo-β-lactamase producing Klebsiella pneumoniae in Tianjin, China
This study shows for the first time the mechanism of carbapenem resistance of a Klebsiella pneumoniae clinical isolate TJ8 recovered from Tianjin Medical University General Hospital ,China. The modified Hodge test and EDTA synergy test were performed for the screening of carbapenemases and metallo-β-lactamases (MBLs), respectively. Polymerase chain reactions and DNA sequencing confirmed that th...
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Despite expansion of the New Delhi metallo-β-lactamase-1 (NDM-1) worldwide, the incident of outbreaks regarding Egypt is still uncommon. In this survey, we denounce the emanation of multidrug-resistant NDM-1-producing Klebsiella pneumoniae in Egypt. We have reclaimed 46 unrepeatable carbapenem-resistant K. pneumoniae isolates at El-demerdash hospital, Ain Shams University, Cairo, Egypt. All the...
متن کاملNew Delhi metallo-β-lactamase-1-producing Klebsiella pneumoniae isolates in hospitalized patients in Kashan, Iran
Background and Objectives New Delhi metallo-ß-lactamase (NDM) is a newly emerging metallo-ß-lactamases, which can destroy all β-lactams including carbapenems. Therefore, this study aimed at evaluating New Delhi metallo-ß-lactamase-1-production in clinical isolates of Klebsiella pneumoniae in Kashan, Iran. Materials and Methods In a cross-sectional study, 181 K. pneumoniae isolates were collec...
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Technical Appendix Figure. Major structural features of plasmid pK351 indicated with bold type, compared with closely related blaNDM-1-positive plasmid pNDM-Ec1GN574 (KJ812998), pKOX_NDM1 KP826710.1). Light gray shades indicate shared regions with a high degree of homology. ORFs are portrayed by arrows and colored according to their putative functions. Dark-blue arrows indicate replication asso...
متن کاملFirst isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil.
A multiresistant Klebsiella pneumoniae isolate was taken from the blood of a 75-year-old patient with nosocomial pneumonia who developed septic shock and failed therapy with imipenem. The isolate presented an MIC of imipenem of 128 microg/ml, and the production of a metallo-beta-lactamase was confirmed by phenotypic and genotypic techniques. We here report, for the first time, the detection of ...
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ژورنال
عنوان ژورنال: Journal of Acute Disease
سال: 2013
ISSN: 2221-6189
DOI: 10.1016/s2221-6189(13)60104-3